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KMID : 0613820120220040532
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Journal of Life Science
2012 Volume.22 No. 4 p.532 ~ p.537
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Cardiovascular Responses to Exercise during Acute Nicotine Abstinence
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Lee Sun-Kyu
Choi Hyun-Min
Kim Jong-Kyung
Kim Chan-Ho
Nho Ho-sung
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Abstract
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We investigated the effect of smoking on cardiovascular responses during acute dynamic exercise. Eleven college students who had been smoking (duration of smoking: 7.45±0.90 years; number of cigarettes per day: 17.72±1.22) participated in this study. All subjects completed a graded exercise testing to determine the relative exercise intensity. The cardiovascular responses were measured at rest, and during mild and moderate exercise immediately, 24, and 48 hours after smoking. The same procedures were repeated during 24-h smoking withdrawal. All subjects were continuously instrumented to measure systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), stroke volume (SV), cardiac output (CO), and total vascular conductance (TVC) at rest and during exercise. The results showed that compared to the nicotine abstention, SBP, DBP, MAP, and HR were significantly higher at 24 and 48 hours after smoking (p<0.05), and CO was significantly higher at rest and during moderate exercise (p<0.05). There were no differences in SV and TVC before and after smoking. Thus, the results suggest that smoking is associated with an exaggerated sympathetic nerve activity during dynamic exercise. Consequently, smoking cessation may help reduce cardiac events, such as stroke and heart attack, during exercise.
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KEYWORD
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Smoking cessation, cardiovascular response, blood pressure, heart rate
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